Best quality Hemocue hemoglobin analyzer - COVID-19 Neutralizing Antibody Rapid Test Kit (Colloidal Gold) – Konsung

Intend Use:

◆For detection of neutralizing antibodies.

◆COVID-19 Neutralizing Antibody Rapid Test Kit (Colloidal Gold) is a lateral flow immunoassay intends for the qualitative detection of neutralizing antibody of SARS-CoV-2 in human whole blood, serum or plasma as an aid in the Evaluation levels of human anti-novel coronavirus neutralizing antibody titer.

Sampling method

◆Whole Blood, Serum, Plasma

Working Principle:

◆This kit uses immunochromatography. The test card contains:1)colloidal gold-labeled recombinant novel coronavirus S-RBD antigen and quality control antibody gold markers; 2) one detection line(T line) and one quality Control line (C line) of nitrocellulose membrane. The T line is immobilized with Human ACE2 protein for detecting novel coronavirus neutralizing antibody and the C line is immobilized with a quality control antibody.

◆When an appropriate amount of the test sample is added to the sample hole of the test card, the sample will move forward along the test card under the action of the capillary. If the sample contains novel coronavirus neutralizing antibody, the antibody will bind to the colloidal gold-labeled novel coronavirus antigen. The rest gold-labeled novel coronavirus antigen in immune complex will be captured by the human ACE2 protein immobilized on

the membrane to form a purple-red T line, the intensity of t line Inversely proportional to the concentration of antibody.

◆The test card also contains a quality control line C .The fuchsia quality control line C should appear regardless of whether a test line appears. If the quality control line C does not appear, the test result is invalid, and the sample needs to be tested again with another test card.

Product detail:

◆Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, or 2019- nCoV) is an enveloped non-segmented positive-sense RNA virus. It is the

cause of COVID-19, which is contagious in humans.

◆SARS-CoV-2 has several structural proteins including spike (S), envelope (E), membrane (M) and nucleocapsid (N). The spike protein (S) contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor, antigens in converting enzyme-2 (ACE2). It is found uman ACE2 receptor leading to endocytosis into the host cells of the deep lung and viral replication.

◆Infection with the SARS-CoV-2 or SARS-COV-2 Vaccine immunization initiates an immune response to produce antibodies which provide protection against future infections from viruses. Human neutralizing antibodies that target the host ACE2 receptor-binding domain (RBD) of the SAR-COV-2 spike protein show promise therapeutically and efficiency protectively.

◆Serum or plasma specimen/ fingertip blood.

◆For semi-quantitative detection of neutralizing antibody.

◆Neutralizing antibody test can detect whether there are neutralizing antibodies against the SARS-CoV-2 in the body.

◆Help track the longevity of protective immunity after vaccination.

Performance

How to use: